prof. dr hab. Andrzej Bojarski

prof. dr hab. Andrzej Bojarski

+48 12 6623365
pokój 325
Zakład Chemii Leków

Dokonania naukowe

  • Publikacje

How can fluorine directly and indirectly affect the hydrogen bonding in molecular systems? - A case study for monofluoroanilines

Autorzy: Pietrus, Wojciech, Kurczab, Rafal, Kafel, Rafal, Machalska, Ewa, Kalinowska-Tluscik, Justyna, Hogendorf, Adam, Zylewski, Marek, Baranska, Malgorzata, Bojarski, Andrzej J.

DOI: 10.1016/J.SAA.2021.119536
Date: 2021-01-01

Multifunctional Ligands with Glycogen Synthase Kinase 3 Inhibitory Activity as a New Direction in Drug Research for Alzheimer's Disease

Autorzy: Jankowska, Agnieszka, Satala, Grzegorz, Bojarski, Andrzej J., Pawlowski, Maciej, Chlon-Rzepa, Grazyna

DOI: 10.2174/0929867327666200427100453
Date: 2021-01-01

Imidazopyridine-Based 5-HT6 Receptor Neutral Antagonists: Impact of N-1-Benzyl and N-1-Phenylsulfonyl Fragments on Different Receptor Conformational States

Autorzy: Vanda, David, Canale, Vittorio, Chaumont-Dubel, Severine, Kurczab, Rafal, Satala, Grzegorz, Koczurkiewicz-Adamczyk, Paulina, Krawczyk, Martyna, Pietrus, Wojciech, Blicharz, Klaudia, Pekala, Elzbieta, Bojarski, Andrzej J., Popik, Piotr, Marin, Philippe, Soural, Miroslav, Zajdel, Pawel

DOI: 10.1021/ACS.JMEDCHEM.0C02009
Date: 2021-01-01

Exploring protein hotspots by optimized fragment pharmacophores

Autorzy: Bajusz, David, Wade, Warren S., Satala, Grzegorz, Bojarski, Andrzej J., Ilas, Janez, Ebner, Jessica, Grebien, Florian, Papp, Henrietta, Jakab, Ferenc, Douangamath, Alice, Fearon, Daren, von Delft, Frank, Schuller, Marion, Ahel, Ivan, Wakefield, Amanda, Vajda, Sandor, Gerencser, Janos, Pallai, Peter, Keseru, Gyoergy M.

DOI: 10.1038/S41467-021-23443-Y
Date: 2021-01-01

Design and Synthesis of Novel Aminoalkanamides Targeting Neurodegeneration and Symptoms of Alzheimer's Disease

Autorzy: Jankowska, Agnieszka, Satala, Grzegorz, Latacz, Gniewomir, Partyka, Anna, Lubelska, Annamaria, Pociecha, Krzysztof, Swierczek, Artur, Wilczynska, Natalia, Mordyl, Barbara, Bojarski, Andrzej J., Wyska, Elzbieta, Chlon-Rzepa, Grazyna

DOI: 10.2174/0929867328666210215113346
Date: 2021-01-01

Tuning the activity of known drugs via the introduction of halogen atoms, a case study of SERT ligands - Fluoxetine and fluvoxamine

Autorzy: Staron, Jakub, Pietrus, Wojciech, Bugno, Ryszard, Kurczab, Rafal, Satala, Grzegorz, Warszycki, Dawid, Lenda, Tomasz, Wantuch, Anna, Hogendorf, Adam S., Hogendorf, Agata, Duszynska, Beata, Bojarski, Andrzej J.

DOI: 10.1016/J.EJMECH.2021.113533
Date: 2021-01-01

Novel medium-sized di(het)areno-fused 1,4,7-(oxa)thiadiazecines as probes for aminergic receptors

Autorzy: Sapegin, Alexander, V, Peshkov, Anatoly A., Kanov, Evgeny, V, Gainetdinov, Raul R., Duszynska, Beata, Bojarski, Andrzej J., Krasavin, Mikhail

DOI: 10.1016/J.MENCOM.2021.07.021
Date: 2021-01-01

Influence of Fluorine Substitution on Nonbonding Interactions in Selected Para-Halogeno Anilines

Autorzy: Pietrus, Wojciech, Kurczab, Rafal, Kalinowska-Tluscik, Justyna, Machalska, Ewa, Golonka, Dominika, Baranska, Malgorzata, Bojarski, Andrzej J.

DOI: 10.1002/CPHC.202100383
Date: 2021-01-01

2D SIFt: a matrix of ligand-receptor interactions

Autorzy: Mordalski, Stefan, Wojtuch, Agnieszka, Podolak, Igor, Kurczab, Rafal, Bojarski, Andrzej J.

DOI: 10.1186/S13321-021-00545-9
Date: 2021-01-01

Rationally designed N-phenylsulfonylindoles as a tool for the analysis of the non-basic 5-HT<sub>6</sub>R ligands binding mode

Autorzy: Staron, Jakub, Bugno, Ryszard, Pietrus, Wojciech, Satala, Grzegorz, Mordalski, Stefan, Warszycki, Dawid, Hogendorf, Agata, Hogendorf, Adam S., Kalinowska-Tluscik, Justyna, Lenda, Tomasz, Pilarski, Bogusiaw, Bojarski, Andrzej J.

DOI: 10.1016/J.EJMECH.2020.112916
Date: 2021-01-01

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