Department of Medicinal Chemistry

Scientific profile

Employees

Professor Andrzej Bojarski, dr hab.

Head

+48 12 6623365

bojarski@if-pan.krakow.pl

room 325

Pracownicy zakładu

Achievements

Publications
Grants

Grant

Development of protocol for in silico design of compounds inhibit Ebola virus infection

Dawid Warszycki, PhD

Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT<inf>1A</inf>receptor agents with anxiolytic-like activity

Bojarski, A.J., Paluchowska, M.H., Duszyńska, B., Bugno, R., Kłodzińska, A., Tatarczyńska, E., Chojnacka-Wójcik, E.

DOI: 10.1016/j.bmc.2005.09.060

Synthesis, anticonvulsant activity and 5-HT1A, 5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione

Obniska, J., Kołaczkowski, M., Bojarski, A.J., Duszyńska, B.

DOI: 10.1016/j.ejmech.2006.03.001

Arylpiperazines with N-acylated amino acids as 5-HT<inf>1A</inf>receptor ligands

Zajdel, P., Subra, G., Bojarski, A.J., Duszyńska, B., Pawłowski, M., Martinez, J.

DOI: 10.1016/j.bmcl.2006.04.035

Synthesis, anticonvulsant properties and 5-HT1A/5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-propyl]-2-aza-spiro[4.4] nonane and [4.5]decane-1,3-dione derivatives

Obniska, J, Kolaczkowski, M, Charakchieva-Minol, S, Nedza, K, Dybala, M, Bojarski, AJ

DOI:

Synthesis, anticonvulsant properties and 5-HT<inf>1A</inf>/5-HT<inf>2A</inf> receptor affinity of new N-[(4-arylpiperazin-1-yl)-propyl]-2-aza-spiro[4.4] nonane and [4.5]decane-1,3-dione derivatives

Obniska, J., Kołaczkowski, M., Charakchieva-Minol, S., Nedza, K., Dybała, M., Bojarski, A.J.

DOI:

Parallel solid-phase synthesis and characterization of new sulfonamide and carboxamide proline derivatives as potential CNS agents

Zajdel, P., Subra, G., Bojarski, A.J., Duszyńska, B., Pawłowski, M., Martinez, J.

DOI: 10.1016/j.bmc.2005.01.060

1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: Synthesis, binding to serotonin (5-HT<inf>1A</inf>, 5-HT<inf>2A</inf>, 5-HT<inf>7</inf>), α<inf>1</inf>-adrenergic, and dopaminergic D<inf>2</inf>receptors, and in vivo 5-HT<inf>1A</inf>functional characteristics

Bojarski, A.J., Paluchowska, M.H., Duszyńska, B., Kłodzińska, A., Tatarczyńska, E., Chojnacka-Wójcik, E.

DOI: 10.1016/j.bmc.2004.12.041

Synthesis and 5-HT<inf>1A</inf>, 5-HT<inf>2A</inf>receptor activity of new β-tetralonohydantoins

Byrtus, H., Pawłowski, M., Czopek, A., Bojarski, A.J., Duszyńska, B., Nowak, G., Kłodzińska, A., Tatarczyńska, E., Wesołowska, A., Chojnacka-Wójcik, E.

DOI: 10.1016/j.ejmech.2004.07.013

Novel, flexible, and conformationally defined analogs of gepirone: Synthesis and 5-HT<inf>1A</inf>, 5-HT<inf>2A</inf>, and D<inf>2</inf>receptor activity

Paluchowska, M.H., Bugno, R., Bojarski, A.J., Charakchieva-Minol, S., Duszyńska, B., Tatarczyńska, E., Kłodzińska, A., Stachowicz, K., Chojnacka-Wójcik, E.

DOI: 10.1016/j.bmc.2004.11.019

Introduction of a new complex imide system into the structure of LCAPs. The synthesis and a 5-HT1A, 5-HT2A and D2 receptor binding study

Kossakowski, J., Raszkiewicz, A., Bugno, R., Bojarski, A.J.

DOI:

Scientific profile

Professor Andrzej Bojarski, dr hab.

Head

Pracownicy zakładu

Ryszard Bugno, dr

Rafał Kurczab, dr hab.

Sabina Podlewska, dr hab.

Grzegorz Satała, dr

Katarzyna Szczepańska, dr

Adam Hogendorf, dr

Katarzyna Kaczorowska, dr

Janusz Malarz, dr

Wojciech Pietruś, dr

Dawid Warszycki, dr

Aneta Kozioł

Krystyna Nędza

Achievements

Grant

Development of protocol for in silico design of compounds inhibit Ebola virus infection

Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT<inf>1A</inf>receptor agents with anxiolytic-like activity

Bojarski, A.J., Paluchowska, M.H., Duszyńska, B., Bugno, R., Kłodzińska, A., Tatarczyńska, E., Chojnacka-Wójcik, E.

Synthesis, anticonvulsant activity and 5-HT1A, 5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione

Obniska, J., Kołaczkowski, M., Bojarski, A.J., Duszyńska, B.

Arylpiperazines with N-acylated amino acids as 5-HT<inf>1A</inf>receptor ligands

Zajdel, P., Subra, G., Bojarski, A.J., Duszyńska, B., Pawłowski, M., Martinez, J.

Synthesis, anticonvulsant properties and 5-HT1A/5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-propyl]-2-aza-spiro[4.4] nonane and [4.5]decane-1,3-dione derivatives

Obniska, J, Kolaczkowski, M, Charakchieva-Minol, S, Nedza, K, Dybala, M, Bojarski, AJ

Synthesis, anticonvulsant properties and 5-HT<inf>1A</inf>/5-HT<inf>2A</inf> receptor affinity of new N-[(4-arylpiperazin-1-yl)-propyl]-2-aza-spiro[4.4] nonane and [4.5]decane-1,3-dione derivatives

Obniska, J., Kołaczkowski, M., Charakchieva-Minol, S., Nedza, K., Dybała, M., Bojarski, A.J.

Parallel solid-phase synthesis and characterization of new sulfonamide and carboxamide proline derivatives as potential CNS agents

Zajdel, P., Subra, G., Bojarski, A.J., Duszyńska, B., Pawłowski, M., Martinez, J.

Bojarski, A.J., Paluchowska, M.H., Duszyńska, B., Kłodzińska, A., Tatarczyńska, E., Chojnacka-Wójcik, E.

Synthesis and 5-HT<inf>1A</inf>, 5-HT<inf>2A</inf>receptor activity of new β-tetralonohydantoins

Byrtus, H., Pawłowski, M., Czopek, A., Bojarski, A.J., Duszyńska, B., Nowak, G., Kłodzińska, A., Tatarczyńska, E., Wesołowska, A., Chojnacka-Wójcik, E.

Novel, flexible, and conformationally defined analogs of gepirone: Synthesis and 5-HT<inf>1A</inf>, 5-HT<inf>2A</inf>, and D<inf>2</inf>receptor activity

Paluchowska, M.H., Bugno, R., Bojarski, A.J., Charakchieva-Minol, S., Duszyńska, B., Tatarczyńska, E., Kłodzińska, A., Stachowicz, K., Chojnacka-Wójcik, E.

Introduction of a new complex imide system into the structure of LCAPs. The synthesis and a 5-HT1A, 5-HT2A and D2 receptor binding study

Kossakowski, J., Raszkiewicz, A., Bugno, R., Bojarski, A.J.

Head

Professor Andrzej Bojarski, dr hab.

See also