Department of Medicinal Chemistry

Scientific profile

Employees

Professor Andrzej Bojarski, dr hab.

Head

+48 12 6623365

bojarski@if-pan.krakow.pl

room 325

Pracownicy zakładu

Achievements

Publications
Grants

Grant

Development of protocol for in silico design of compounds inhibit Ebola virus infection

Dawid Warszycki, PhD

PRELIMINARY EVALUATION OF CENTRAL NERVOUS SYSTEM ACTIVITY OF (E)-N-2-METHYL-3-PHENYLPROP-2-ENYL ((E)-N-α-METHYLCIN-NAMYL) DERIVATIVES OF SELECTED AMINOALKANOLS

Gunia-Krzyzak, Agnieszka, Pytka, Karolina, Sloczynska, Karolina, Waszkielewicz, Anna. M., Satala, Grzegorz, Bojarski, Andrzej J., Sapa, Jacek, Filipek, Barbara, Cegla, Marek, Pekala, Elzbieta, Marona, Henryk

DOI:

Arylsulfonamide derivatives of (aryloxy)ethylpiperidines as selective 5-HT<inf>7</inf> receptor antagonists and their psychotropic properties

Zajdel, P., Canale, V., Partyka, A., Marciniec, K., Kurczab, R., Satała, G., Siwek, A., Jastrzębska-Więsek, M., Wesołowska, A., Kos, T., Popik, P., Bojarski, A.J.

DOI: 10.1039/c5md00166h

Fingerprint-based consensus virtual screening towards structurally new 5-HT<inf>6</inf>R ligands

Smusz, S., Kurczab, R., Satała, G., Bojarski, A.J.

DOI: 10.1016/j.bmcl.2015.03.049

Towards novel 5-HT<inf>7</inf> versus 5-HT<inf>1A</inf> receptor ligands among LCAPs with cyclic amino acid amide fragments: Design, synthesis, and antidepressant properties. Part II

Canale, V., Kurczab, R., Partyka, A., SataÅa, G., Witek, J., Jastrzäbska-Wiäsek, M., Pawåowski, M., Bojarski, A.J., WesoÅowska, A., Zajdel, P.

DOI: 10.1016/j.ejmech.2014.12.041

IP562083 a novel mGluR7 negative allosteric modulator

Branski, Piotr, Burnat, Grzegorz, Stankiewicz, Anna, Bugno, Ryszard, Paluchowska, Maria, Kaczorowska, Katarzyna, Chruscicka, Barbara, Bojarski, Andrzej, Pilc, Andrzej

DOI: 10.1016/J.PHAREP.2015.06.055

Ligand-Based Virtual Screening in a Search for Novel Anti-HIV-1 Chemotypes

Kurczyk, A., Warszycki, D., Musiol, R., Kafel, R., Bojarski, A.J., Polanski, J.

DOI: 10.1021/acs.jcim.5b00295

Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT<inf>1A</inf>receptor functional profile

Partyka, A., Chłoń-Rzepa, G., Wasik, A., Jastrzębska-Więsek, M., Bucki, A., Kołaczkowski, M., Satała, G., Bojarski, A.J., Wesołowska, A.

DOI: 10.1016/j.bmc.2014.11.008

Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT<inf>1A</inf> activity. part 5

Gomolka, A., Ciesielska, A., Wróbel, M.Z., Chodkowski, A., Kleps, J., Dawidowski, M., Siwek, A., Wolak, M., Stachowicz, K., Slawinska, A., Nowak, G., Satala, G., Bojarski, A.J., Belka, M., Ulenberg, S., Baczek, T., Skowronek, P., Turlo, J., Herold, F.

DOI: 10.1016/j.ejmech.2015.05.003

Arylsulfonamide derivatives of (aryloxy)ethylpiperidines as selective 5-HT<inf>7</inf>receptor antagonists and their psychotropic properties

Zajdel, P., Canale, V., Partyka, A., Marciniec, K., Kurczab, R., Satała, G., Siwek, A., Jastrzębska-Więsek, M., Wesołowska, A., Kos, T., Popik, P., Bojarski, A.J.

DOI: 10.1039/c5md00166h

Towards novel 5-HT<inf>7</inf>versus 5-HT<inf>1A</inf>receptor ligands among LCAPs with cyclic amino acid amide fragments: Design, synthesis, and antidepressant properties. Part II

Canale, V., Kurczab, R., Partyka, A., SataÅa, G., Witek, J., Jastrzäbska-Wiäsek, M., Pawåowski, M., Bojarski, A.J., WesoÅowska, A., Zajdel, P.

DOI: 10.1016/j.ejmech.2014.12.041

Scientific profile

Professor Andrzej Bojarski, dr hab.

Head

Pracownicy zakładu

Ryszard Bugno, dr

Rafał Kurczab, dr hab.

Sabina Podlewska, dr hab.

Grzegorz Satała, dr

Katarzyna Szczepańska, dr

Adam Hogendorf, dr

Katarzyna Kaczorowska, dr

Janusz Malarz, dr

Wojciech Pietruś, dr

Dawid Warszycki, dr

Aneta Kozioł

Krystyna Nędza

Achievements

Grant

Development of protocol for in silico design of compounds inhibit Ebola virus infection

PRELIMINARY EVALUATION OF CENTRAL NERVOUS SYSTEM ACTIVITY OF (<i>E</i>)-<i>N</i>-2-METHYL-3-PHENYLPROP-2-ENYL ((<i>E</i>)-<i>N</i>-α-METHYLCIN-NAMYL) DERIVATIVES OF SELECTED AMINOALKANOLS

Gunia-Krzyzak, Agnieszka, Pytka, Karolina, Sloczynska, Karolina, Waszkielewicz, Anna. M., Satala, Grzegorz, Bojarski, Andrzej J., Sapa, Jacek, Filipek, Barbara, Cegla, Marek, Pekala, Elzbieta, Marona, Henryk

Arylsulfonamide derivatives of (aryloxy)ethylpiperidines as selective 5-HT<inf>7</inf> receptor antagonists and their psychotropic properties

Zajdel, P., Canale, V., Partyka, A., Marciniec, K., Kurczab, R., Satała, G., Siwek, A., Jastrzębska-Więsek, M., Wesołowska, A., Kos, T., Popik, P., Bojarski, A.J.

Fingerprint-based consensus virtual screening towards structurally new 5-HT<inf>6</inf>R ligands

Smusz, S., Kurczab, R., Satała, G., Bojarski, A.J.

Towards novel 5-HT<inf>7</inf> versus 5-HT<inf>1A</inf> receptor ligands among LCAPs with cyclic amino acid amide fragments: Design, synthesis, and antidepressant properties. Part II

Canale, V., Kurczab, R., Partyka, A., SataÅa, G., Witek, J., Jastrzäbska-Wiäsek, M., Pawåowski, M., Bojarski, A.J., WesoÅowska, A., Zajdel, P.

IP562083 a novel mGluR7 negative allosteric modulator

Branski, Piotr, Burnat, Grzegorz, Stankiewicz, Anna, Bugno, Ryszard, Paluchowska, Maria, Kaczorowska, Katarzyna, Chruscicka, Barbara, Bojarski, Andrzej, Pilc, Andrzej

Ligand-Based Virtual Screening in a Search for Novel Anti-HIV-1 Chemotypes

Kurczyk, A., Warszycki, D., Musiol, R., Kafel, R., Bojarski, A.J., Polanski, J.

Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT<inf>1A</inf>receptor functional profile

Partyka, A., Chłoń-Rzepa, G., Wasik, A., Jastrzębska-Więsek, M., Bucki, A., Kołaczkowski, M., Satała, G., Bojarski, A.J., Wesołowska, A.

Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT<inf>1A</inf> activity. part 5

Gomolka, A., Ciesielska, A., Wróbel, M.Z., Chodkowski, A., Kleps, J., Dawidowski, M., Siwek, A., Wolak, M., Stachowicz, K., Slawinska, A., Nowak, G., Satala, G., Bojarski, A.J., Belka, M., Ulenberg, S., Baczek, T., Skowronek, P., Turlo, J., Herold, F.

Arylsulfonamide derivatives of (aryloxy)ethylpiperidines as selective 5-HT<inf>7</inf>receptor antagonists and their psychotropic properties

Zajdel, P., Canale, V., Partyka, A., Marciniec, K., Kurczab, R., Satała, G., Siwek, A., Jastrzębska-Więsek, M., Wesołowska, A., Kos, T., Popik, P., Bojarski, A.J.

Towards novel 5-HT<inf>7</inf>versus 5-HT<inf>1A</inf>receptor ligands among LCAPs with cyclic amino acid amide fragments: Design, synthesis, and antidepressant properties. Part II

Canale, V., Kurczab, R., Partyka, A., SataÅa, G., Witek, J., Jastrzäbska-Wiäsek, M., Pawåowski, M., Bojarski, A.J., WesoÅowska, A., Zajdel, P.

Head

Professor Andrzej Bojarski, dr hab.

See also