Department of Medicinal Chemistry

Scientific profile

Employees

Professor Andrzej Bojarski, dr hab.

Head

+48 12 6623365

bojarski@if-pan.krakow.pl

room 325

Pracownicy zakładu

Achievements

Publications
Grants

Grant

Development of protocol for in silico design of compounds inhibit Ebola virus infection

Dawid Warszycki, PhD

Sonication-Assisted Synthesis of (E)-2-Methyl-but-2-enyl Nucleoside Phosphonate Prodrugs

Bessières, M., Sari, O., Roy, V., Warszycki, D., Bojarski, A.J., Nolan, S.P., Snoeck, R., Andrei, G., Schinazi, R.F., Agrofoglio, L.A.

DOI: 10.1002/slct.201600879

Erratum: Synthesis of Some Aminophosphonates Bearing N-(Fluorophenyl)-piperazynyl Moiety and Their Activity toward Serotonin Receptors (Heteroatom Chemistry (2015) 26:4 (290-298) DOI: 10.1002/hc.21259)

Lewki, J., Jóźwiak, A., Tokarz, P., Zagórski, P.M., Cal, D., Satała, G., Bojarski, A.J.

DOI: 10.1002/hc.21312

Halogen bonding enhances activity in a series of dual 5-HT<inf>6</inf>/D<inf>2</inf>ligands designed in a hybrid bioisostere generation/virtual screening protocol

Staroń, J., Warszycki, D., Kurczab, R., Satała, G., Bugno, R., Hogendorf, A., Bojarski, A.J.

DOI: 10.1039/c6ra08714k

GPCRdb: the G protein-coupled receptor database – an introduction

Munk, C., Isberg, V., Mordalski, S., Harpsøe, K., Rataj, K., Hauser, A.S., Kolb, P., Bojarski, A.J., Vriend, G., Gloriam, D.E.

DOI: 10.1111/bph.13509

Concentration-Dependent Dual Mode of Zn Action at Serotonin 5-HT1A Receptors: In Vitro and In Vivo Studies

Satała, G., Duszyńska, B., Stachowicz, K., Rafalo, A., Pochwat, B., Luckhart, C., Albert, P.R., Daigle, M., Tanaka, K.F., Hen, R., Lenda, T., Nowak, G., Bojarski, A.J., Szewczyk, B.

DOI: 10.1007/s12035-015-9586-3

Towards new 5-HT<inf>7</inf>antagonists among arylsulfonamide derivatives of (aryloxy)ethyl-alkyl amines: Multiobjective based design, synthesis, and antidepressant and anxiolytic properties

Canale, V., Kurczab, R., Partyka, A., Sataa, G., Ledna, T., Jastrzebska-Wiesek, M., Wesoowska, A., Bojarski, A.J., Zajdel, P.

DOI: 10.1016/j.ejmech.2015.11.040

N1-Azinylsulfonyl-1H-indoles: 5-HT6 Receptor Antagonists with Procognitive and Antidepressant-Like Properties

Zajdel, P., Marciniec, K., Satała, G., Canale, V., Kos, T., Partyka, A., Jastrzȩbska-Wiȩsek, M., Wesołowska, A., Basińska-Ziobroń, A., Wójcikowski, J., Daniel, W.A., Bojarski, A.J., Popik, P.

DOI: 10.1021/acsmedchemlett.6b00056

N-Alkylated arylsulfonamides of (aryloxy)ethyl piperidines: 5-HT<inf>7</inf>receptor selectivity versus multireceptor profile

Canale, V., Kurczab, R., Partyka, A., Satała, G., Słoczyńska, K., Kos, T., Jastrzębska-Więsek, M., Siwek, A., Pękala, E., Bojarski, A.J., Wesołowska, A., Popik, P., Zajdel, P.

DOI: 10.1016/j.bmc.2015.11.041

Synthesis and structure-activity relationship analysis of 5-HT<inf>7</inf> receptor antagonists: Piperazin-1-yl substituted unfused heterobiaryls

Strekowski, L., Saczewski, J., Raux, E.A., Fernando, N.T., Klenc, J., Paranjpe, S., Raszkiewicz, A., Blake, A.L., Ehalt, A.J., Barnes, S., Baranowski, T.C., Sullivan, S.M., Satała, G., Bojarski, A.J.

DOI: 10.3390/molecules21040433

Novel 1H-Pyrrolo[3,2-c]quinoline Based 5-HT<inf>6</inf>Receptor Antagonists with Potential Application for the Treatment of Cognitive Disorders Associated with Alzheimer's Disease

Grychowska, K., Satała, G., Kos, T., Partyka, A., Colacino, E., Chaumont-Dubel, S., Bantreil, X., Wesołowska, A., Pawłowski, M., Martinez, J., Marin, P., Subra, G., Bojarski, A.J., Lamaty, F., Popik, P., Zajdel, P.

DOI: 10.1021/acschemneuro.6b00090

Scientific profile

Professor Andrzej Bojarski, dr hab.

Head

Pracownicy zakładu

Ryszard Bugno, dr

Rafał Kurczab, dr hab.

Sabina Podlewska, dr hab.

Grzegorz Satała, dr

Katarzyna Szczepańska, dr

Adam Hogendorf, dr

Katarzyna Kaczorowska, dr

Janusz Malarz, dr

Wojciech Pietruś, dr

Dawid Warszycki, dr

Aneta Kozioł

Krystyna Nędza

Achievements

Grant

Development of protocol for in silico design of compounds inhibit Ebola virus infection

Sonication-Assisted Synthesis of (E)-2-Methyl-but-2-enyl Nucleoside Phosphonate Prodrugs

Bessières, M., Sari, O., Roy, V., Warszycki, D., Bojarski, A.J., Nolan, S.P., Snoeck, R., Andrei, G., Schinazi, R.F., Agrofoglio, L.A.

Erratum: Synthesis of Some Aminophosphonates Bearing N-(Fluorophenyl)-piperazynyl Moiety and Their Activity toward Serotonin Receptors (Heteroatom Chemistry (2015) 26:4 (290-298) DOI: 10.1002/hc.21259)

Lewki, J., Jóźwiak, A., Tokarz, P., Zagórski, P.M., Cal, D., Satała, G., Bojarski, A.J.

Halogen bonding enhances activity in a series of dual 5-HT<inf>6</inf>/D<inf>2</inf>ligands designed in a hybrid bioisostere generation/virtual screening protocol

Staroń, J., Warszycki, D., Kurczab, R., Satała, G., Bugno, R., Hogendorf, A., Bojarski, A.J.

GPCRdb: the G protein-coupled receptor database – an introduction

Munk, C., Isberg, V., Mordalski, S., Harpsøe, K., Rataj, K., Hauser, A.S., Kolb, P., Bojarski, A.J., Vriend, G., Gloriam, D.E.

Concentration-Dependent Dual Mode of Zn Action at Serotonin 5-HT1A Receptors: In Vitro and In Vivo Studies

Satała, G., Duszyńska, B., Stachowicz, K., Rafalo, A., Pochwat, B., Luckhart, C., Albert, P.R., Daigle, M., Tanaka, K.F., Hen, R., Lenda, T., Nowak, G., Bojarski, A.J., Szewczyk, B.

Towards new 5-HT<inf>7</inf>antagonists among arylsulfonamide derivatives of (aryloxy)ethyl-alkyl amines: Multiobjective based design, synthesis, and antidepressant and anxiolytic properties

Canale, V., Kurczab, R., Partyka, A., Sataa, G., Ledna, T., Jastrzebska-Wiesek, M., Wesoowska, A., Bojarski, A.J., Zajdel, P.

N1-Azinylsulfonyl-1H-indoles: 5-HT6 Receptor Antagonists with Procognitive and Antidepressant-Like Properties

Zajdel, P., Marciniec, K., Satała, G., Canale, V., Kos, T., Partyka, A., Jastrzȩbska-Wiȩsek, M., Wesołowska, A., Basińska-Ziobroń, A., Wójcikowski, J., Daniel, W.A., Bojarski, A.J., Popik, P.

N-Alkylated arylsulfonamides of (aryloxy)ethyl piperidines: 5-HT<inf>7</inf>receptor selectivity versus multireceptor profile

Canale, V., Kurczab, R., Partyka, A., Satała, G., Słoczyńska, K., Kos, T., Jastrzębska-Więsek, M., Siwek, A., Pękala, E., Bojarski, A.J., Wesołowska, A., Popik, P., Zajdel, P.

Synthesis and structure-activity relationship analysis of 5-HT<inf>7</inf> receptor antagonists: Piperazin-1-yl substituted unfused heterobiaryls

Strekowski, L., Saczewski, J., Raux, E.A., Fernando, N.T., Klenc, J., Paranjpe, S., Raszkiewicz, A., Blake, A.L., Ehalt, A.J., Barnes, S., Baranowski, T.C., Sullivan, S.M., Satała, G., Bojarski, A.J.

Novel 1H-Pyrrolo[3,2-c]quinoline Based 5-HT<inf>6</inf>Receptor Antagonists with Potential Application for the Treatment of Cognitive Disorders Associated with Alzheimer's Disease

Grychowska, K., Satała, G., Kos, T., Partyka, A., Colacino, E., Chaumont-Dubel, S., Bantreil, X., Wesołowska, A., Pawłowski, M., Martinez, J., Marin, P., Subra, G., Bojarski, A.J., Lamaty, F., Popik, P., Zajdel, P.

Head

Professor Andrzej Bojarski, dr hab.

See also