Department of Phytochemistry

Scientific profile
- About department
- Employees
- Laboratories
Our studies are focused on biologically active secondary metabolites from plants and plant tissue cultures, with special interest in compounds biosynthesized by the plants of Cichorieae and Inuleae tribes (Asteraceae family). Recently, we have been investigating formerly unexamined Lactuca species of African and Asian origin, in a search of antioxidative and anti-inflammatory compounds.
Scope of research
- plant secondary metabolites – isolation and structure identification/elucidation,
- qualitative and quantitative analysis of bioactive compounds in a plant material,
- regulation of plant metabolism in vitro and in vivo,
- bioactivity assays,
- tissue cultures of medicinal plants.
In cooperation with other research teams and institutions we perform analyses of selected compounds in a plant material of different origin, provide pure compounds for bioactivity evaluation and share plant materials for biological studies.
Professor Anna Stojakowska, dr hab.
Head
Pracownicy zakładu
Klaudia Michalska, dr hab.
Beata Duszyńska, dr
Katarzyna Kozynacka, mgr
Weronika Strumińska
Józef Wójtowicz
Małgorzata Tomera
Anna Sochacka-Obruśnik, mgr inż.
Pracownicy pracowni
Achievements
- Publications
Further sesquiterpenoids and phenolics from two species of Taraxacum F.H. Wigg. and cytotoxic activity of taraxinic acid and its derivatives
Klaudia Michalska, Agnieszka Galanty, Oskar Michalski, Anna Stojakowska
DOI: 10.1016/j.phytol.2019.02.010
Professor Wanda Kisiel (1946–2018) in memoriam
DOI: 10.2478/hepo-2018-0007
Major terpenoids from Telekia speciosa flowers and their cytotoxic activity in vitro
Stojakowska, A., Galanty, A., Malarz, J., Michalik, M.
DOI: 10.1080/14786419.2018.1437431
Thymol derivatives from the roots of Xerolekia speciosissima an endemic species of the pre-Alpine area
Kłeczek, N., Malarz, J., Kosecka-Strojek, M., Musielak, B., Stojakowska, A.
DOI: 10.1016/j.phytol.2019.01.010
Secondary Metabolism in Tissue and Organ Cultures of Plants from the Tribe Cichorieae
Stojakowska, A., Malarz, J.
DOI: 10.1007/978-3-030-11253-0_23-1
Natural products from Tolpis barbata (L.) Gaertn. (Asteraceae, Cichorieae)
Michalska, K., Malarz, J., Paul, W., Stojakowska, A.
DOI: 10.1016/j.bse.2019.103922
Eupatoriopicrin Inhibits Pro-inflammatory Functions of Neutrophils via Suppression of IL-8 and TNF-alpha Production and p38 and ERK 1/2 MAP Kinases.
Michalak B, Piwowarski JP, Granica S, Waltenberger B, Atanasov AG, Khan SY, Breuss JM, Uhrin P, Żyżyńska-Granica B, Stojakowska A, Stuppner H, Kiss AK
DOI: 10.1021/acs.jnatprod.8b00939
Does co-inoculation of Lactuca serriola with endophytic and arbuscular mycorrhizal fungi improve plant growth in a polluted environment?
Ważny, R., Rozpądek, P., Jędrzejczyk, R.J., Śliwa, M., Stojakowska, A., Anielska, T., Turnau, K.
DOI: 10.1007/s00572-018-0819-y
Phenolics and terpenoids from a wild edible plant Lactuca orientalis (Boiss.) Boiss.: A preliminary study
Stojakowska, A., Michalska, K., Kłeczek, N., Malarz, J., Beharav, A.
DOI: 10.1016/j.jfca.2018.01.024
Bioactive phenolics from in vitro cultures of Lactuca aculeata Boiss. et Kotschy
Stojakowska, A., Malarz, J.
DOI: 10.1016/j.phytol.2016.11.003