Scientific profile

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Our studies are focused on biologically active secondary metabolites from plants and plant tissue cultures, with special interest in compounds biosynthesized by the plants of Cichorieae and Inuleae tribes (Asteraceae family). Recently, we have been investigating formerly unexamined Lactuca species of African and Asian origin, in a search of antioxidative and anti-inflammatory compounds.

Scope of research

  • plant secondary metabolites – isolation and structure identification/elucidation,
  • qualitative and quantitative analysis of bioactive compounds in a plant material,
  • regulation of plant metabolism in vitro and in vivo,
  • bioactivity assays,
  • tissue cultures of medicinal plants.

In cooperation with other research teams and institutions we perform analyses of selected compounds in a plant material of different origin, provide pure compounds for bioactivity evaluation and share plant materials for biological studies.

Achievements

  • Publications

Stem Lettuce and Its Metabolites: Does the Variety Make Any Difference?

Janusz Malarz, Klaudia Michalska, Anna Stojakowska

DOI: 10.3390/foods10010059

Neuroprotective Effects of Methyl Caffeate against Hydrogen Peroxide-Induced Cell Damage: Involvement of Caspase 3 and Cathepsin D Inhibition

Danuta Jantas, Jakub Chwastek, Janusz Malarz, Anna Stojakowska, Władysław Lasoń

DOI: 10.3390/biom10111530

Constituents of Xerolekia speciosissima (L.) Anderb. (Inuleae), and Anti-Inflammatory Activity of 7,10-Diisobutyryloxy-8,9-epoxythymyl Isobutyrate

Natalia Kłeczek, Janusz Malarz, Barbara Gierlikowska, Anna K. Kiss, Anna Stojakowska

DOI: 10.3390/molecules25214913

Variation of sesquiterpene lactone contents in Lactuca altaica natural populations from Armenia

Beharav, A., Malarz, J., Michalska, K., Ben-David, R., Stojakowska, A.

DOI: 10.1016/j.bse.2020.104030

Associations between root-inhabiting fungi and 40 species of medicinal plants with potential applications in the pharmaceutical and biotechnological industries

Piotr Piszczek, Karolina Kuszewska, Janusz Błaszkowski, Anna Sochacka-Obruśnik, Anna Stojakowska, Szymon Zubek

DOI: 10.1016/j.apsoil.2019.01.018

Carpesium divaricatum Sieb. & Zucc. Revisited: Newly Identified Constituents from Aerial Parts of the Plant and Their Possible Contribution to the Biological Activity of the Plant

Natalia Kłeczek, Barbara Michalak, Janusz Malarz, Anna Karolina Kiss, Anna Stojakowska

DOI: 10.3390/molecules24081614

See also