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Department of Phytochemistry
Scientific profile
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Our studies are focused on biologically active secondary metabolites from plants and plant tissue cultures, with special interest in compounds biosynthesized by the plants of Cichorieae and Inuleae tribes (Asteraceae family). Recently, we have been investigating formerly unexamined Lactuca species of African and Asian origin, in a search of antioxidative and anti-inflammatory compounds.
Scope of research
- plant secondary metabolites – isolation and structure identification/elucidation,
- qualitative and quantitative analysis of bioactive compounds in a plant material,
- regulation of plant metabolism in vitro and in vivo,
- bioactivity assays,
- tissue cultures of medicinal plants.
In cooperation with other research teams and institutions we perform analyses of selected compounds in a plant material of different origin, provide pure compounds for bioactivity evaluation and share plant materials for biological studies.
Professor Anna Stojakowska, dr hab.
Head
+48 12 6623254
stoja@if-pan.krakow.pl
room Radzikowskiego 176 Pracownicy zakładu
Klaudia Michalska, dr hab.
+48 12 6623257klaudiaz@if-pan.krakow.plroom Radzikow.Beata Duszyńska, dr
+48 12 6623349duszyn@if-pan.krakow.plroom 325Katarzyna Kozynacka, mgr
+48 12 6623257steck@if-pan.krakow.plroom Radzikow.Weronika Strumińska
+48 12 6623257strum@if-pan.krakow.plJózef Wójtowicz
+48 12 6623257room Radzikow.Anna Sochacka-Obruśnik, mgr inż.
+48 12 6623257sochacka@if-pan.krakow.plroom Radzikow.Pracownicy pracowni
Achievements
- Publications
Polish Achievements in Bioactive Compound Production From In Vitro Plant Cultures
DOI: 10.5586/asbp.9110
Hairy Root Cultures as a Source of Polyphenolic Antioxidants: Flavonoids, Stilbenoids and Hydrolyzable Tannins
Janusz Malarz, Klaudia Michalska, Yulia V. Yudina, Anna Stojakowska
DOI: 10.3390/plants11151950
From Monographs to Chromatograms: The Antimicrobial Potential of Inula helenium L. (Elecampane) Naturalised in Ireland
Ciara-Ruth Kenny, Anna Stojakowska, Ambrose Furey, Brigid Lucey
DOI: 10.3390/molecules27041406
Neuroprotective Properties of Kempferol Derivatives from Maesa membranacea against Oxidative Stress-Induced Cell Damage: An Association with Cathepsin D Inhibition and PI3K/Akt Activation
Danuta Jantas, Janusz Malarz, Thanh Nguyen Le, Anna Stojakowska
DOI: 10.3390/ijms221910363
The contribution of phenolics to the anti-inflammatory potential of the extract from Bolivian coriander (Porophyllum ruderale subsp. ruderale).
DOI: 10.1016/j.foodchem.2021.131116
Germacranolides from Carpesium divaricatum: Some New Data on Cytotoxic and Anti-Inflammatory Activity
Natalia Kłeczek, Janusz Malarz, Barbara Gierlikowska, Łukasz Skalniak, Agnieszka Galanty, Anna K. Kiss, Anna Stojakowska
DOI: 10.3390/molecules26154644
Design, Sustainable Synthesis and Biological Evaluation of a Novel Dual α2A/5-HT7 Receptor Antagonist with Antidepressant-Like Properties
Vittorio Canale, Magdalena Kotańska, Anna Dziubina, Matylda Stefaniak, Agata Siwek, Gabriela Starowicz, Krzysztof Marciniec, Patryk Kasza, Grzegorz Satała, Beata Duszyńska, Xavier Bantreil, Frédéric Lamaty, Marek Bednarski, Jacek Sapa, Paweł Zajdel
DOI: 10.3390/molecules26133828
Chemical constituents from <i>Lactuca plumieri</i> (L.) Gren. & Godr. (Asteraceae).
DOI: 10.1080/14786419.2021.1920583
Composition of Essential Oils from Roots and Aerial Parts of Carpesium cernuum and Their Antibacterial and Cytotoxic Activities
Anna Wajs-Bonikowska, Janusz Malarz, Łukasz Szoka, Paweł Kwiatkowski, Anna Stojakowska
DOI: 10.3390/molecules26071883
Synthesis of Novel Pyrido[1,2-<i>c</i>]pyrimidine Derivatives with 6-Fluoro-3-(4-piperidynyl)-1,2-benzisoxazole Moiety as Potential SSRI and 5-HT<sub>1A</sub> Receptor Ligands
Marek Król, Grzegorz Ślifirski, Jerzy Kleps, Szymon Ulenberg, Mariusz Belka, Tomasz Bączek, Agata Siwek, Katarzyna Stachowicz, Bernadeta Szewczyk, Gabriel Nowak, Beata Duszyńska, Franciszek Herold
DOI: 10.3390/ijms22052329