Department of Brain Biochemistry

Scientific profile

  • Employees
  • Laboratories
Grzegorz Kreiner

Grzegorz Kreiner, dr hab.

Head

+48 12 6623335
room 40

Pracownicy zakładu

Professor Irena Nalepa, dr hab.

+48 12 6623225
room 39

Katarzyna Kuter-Nowak, dr hab.

+48 12 6623226
room 3.36

Elżbieta Lorenc-Koci, dr hab.

+48 12 6623272
room 338

Piotr Chmielarz, dr

+48 12 6623227
room 37A

Danuta Jantas, dr hab.

+48 12 3343721
room 2.1

Agnieszka Zelek-Molik, dr

+48 12 6623227
room 36

Joanna Kula, dr

+48 12 6623286
room 337

Justyna Barut, dr

+48 12 6623245
room 43

Adam Bielawski, dr

+48 12 6623381
room 37

Jolanta Konieczny, dr

+48 12 6623272
room 338

Katarzyna Rafa-Zabłocka, dr

+48 12 6623227
room 36

Katarzyna Maziarz, mgr

+48 12 6623245
room 43

Michał Wilczkowski, mgr

+48 12 6623245
room 43

Anna Alwani, mgr

+48 12 662 32 45
room 43

Tomasz Lenda, mgr

+48 12 3343709
room 340

Agata Maziak, dr

+48 12 6623383
room 340

Emilija Napieralska, mgr

+48 12 3623286
room 3.37

Pracownicy pracowni

Katarzyna Kuter-Nowak, dr hab.

+48 12 6623226
room 3.36

Elżbieta Lorenc-Koci, dr hab.

+48 12 6623272
room 338

Joanna Kula, dr

+48 12 6623286
room 337

Tomasz Lenda, mgr

+48 12 3343709
room 340

Agata Maziak, dr

+48 12 6623383
room 340

Emilija Napieralska, mgr

+48 12 3623286
room 3.37

Laboratory of Neurodegeneration and Experimental Therapy

Headdr hab. Katarzyna Kuter-Nowak

Achievements

  • Publications
  • Grants
  • Awards

Grant

The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopamine receptor ligands

Danuta Jantas, PhD

Grant

PASIFIC Call 1 TheraLanOx "Neuroprotective properties of theranostic lanthanide oxide nanoparticles against neurotoxin-induced cellular models of Parkinson’s disease"

Rugmani Meenambal, PhD

Grant

Hybrid carbon composites for stimulation of cells of the central nervous system

Danuta Jantas, PhD

Grant

Evaluation of the influence of progressive noradrenergic neurodegeneration on dopaminergic system functioning in context of presymptomatic phase of Parkinson's disease

Grzegorz Kreiner, PhD

Grant

Różnicowanie udziału trzech podtypów receptora alfa(1)-adrenergicznego w efektach leków przeciwdepresyjnych: badania w oparciu o genetyczne modele in vitro oraz in vivo OPUS9 2015/17/B/NZ7/03018

Professor Irena Nalepa, PhD

Grant

Zanieczyszczenia powietrza a choroby autoimmunologiczne: rola wielofazowej chemii nieorganicznej SYMFONIA3: APARIC 2015/16/W/ST5/00005

Professor Irena Nalepa, PhD

Grant

Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment

Grzegorz Kreiner, PhD

Grant

The study on the role of metabotropic glutamate receptor subtype 8 (mGluR8) in cancer cells - potential target for new anticancer drugs

Danuta Jantas, PhD

Grant

Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodegeneration, based on tissue specific inducible Cre/loxP system

Grzegorz Kreiner, PhD

Grant

The study on the neuroprotective potential of metabotropic glutamate group II and III receptors in in vitro and in vivo apoptosis models

Danuta Jantas, PhD

Grant

Badanie interakcji szlaków sygnałowych: receptory alfa1-adrenergiczne – stres komórkowy – apoptoza, w modelu chronicznego łagodnego stresu - zadanie 1.4 POIG.01.01.02-12-004/09 DeMeTer (Depresja – Mechanizmy – Terapia) Działanie 1.1 Poddziałanie 1.1.2. Zadanie główne: Modelowanie depresji – strategia poznawania jej etiologii.

Professor Irena Nalepa, PhD

Grant

Badanie interakcji układu noradrenergicznego i glukokortykoidowego w nowym modelu genetycznym i ocena jego przydatności jako modelu depresji u myszy - zadanie 1.2 POIG 01.01.02-12-004/09 DeMeTer (Depresja – Mechanizmy – Terapia). Działanie 1.1 Poddziałanie 1.1.2. Zadanie główne: Modelowanie depresji – strategia poznawania jej etiologii.

Grzegorz Kreiner, PhD

Grant

Funkcja in vitro: funkcjonalna aktywność nowych ligandów receptora serotoninowego 5HT(6) i dopaminowego D(2) na poziomie modulacji odpowiedzi wtórnych przekaźników zadanie nr 6 GRANT POIG ProKog Nr UDA-POIG.01.03.01-12-063/09-02 Działanie 1.3, Poddziałanie 1.3.1: Antagoniści receptora 5HT(6): nowoczesne leki przeciwpsychotyczne o dodatkowym działaniu prokognitywnym

Professor Irena Nalepa, PhD

Award

2020 - Bronze Cross of Merit from President of Poland; for significant contribution to science development in Poland

Danuta Jantas, PhD

Award

Team Scientific Award of the 5th Medical Sciences PAS for a series of 3 publications "The role of astrocytes in mechanisms compensating for the degeneration of dopaminergic neurons and in the regulation of cellular energy of the black-striatal system in an animal model of early Parkinson's disease"

Katarzyna Kuter - Nowak, PhD

Award

2009 - Young Investigator Award, Neuropeptides Festival, Salzburg, Austria.

Danuta Jantas, PhD

Award

Award for publication woth high IF in 2018 granted by the Head of the Institute of Pharmacology

Katarzyna Kuter - Nowak, PhD

Inactivation of glucocorticoid receptor in noradrenergic system influences anxiety- and depressive-like behavior in mice

Chmielarz, P., Kus̈mierczyk, J., Parlato, R., Schütz, G., Nalepa, I., Kreiner, G.

DOI: 10.1371/journal.pone.0072632

Acute and repeated treatment with the 5-HT<inf>7</inf> receptor antagonist SB 269970 induces functional desensitization of 5-HT<inf>7</inf> receptors in rat hippocampus

Tokarski, K., Zelek-Molik, A., Duszyńska, B., Satała, G., Bobula, B., Kusek, M., Chmielarz, P., Nalepa, I., Hess, G.

DOI: 10.1016/S1734-1140(12)70763-6

Effects of co-administration of fluoxetine and risperidone on properties of peritoneal and pleural macrophages in rats subjected to the forced swimming test

Roman, A., Kuśmierczyk, J., Klimek, E., Rogóz, Z., Nalepa, I.

DOI: 10.1016/S1734-1140(12)70934-9

Morphine-induced place preference affects mRNA expression of G protein α subunits in rat brain

Zelek-Molik, A., Bielawski, A., Kreiner, G., Popik, P., Vetulani, J., Nalepa, I.

DOI: 10.1016/S1734-1140(12)70850-2

Effects of the noradrenergic neurotoxin DSP-4 on the expression of α<inf>1</inf>-adrenoceptor subtypes after antidepressant treatment

Kreiner, G., Zelek-Molik, A., Kowalska, M., Bielawski, A., Antkiewicz-Michaluk, L., Nalepa, I.

DOI: 10.1016/S1734-1140(11)70699-5

Changes induced by formalin pain in central α<inf>1</inf>- adrenoceptor density are modulated by adenosine receptor agonists

Nalepa, I., Vetulani, J., Borghi, V., Kowalska, M., Przewłocka, B., Roman, A., Pavone, F.

DOI: 10.1007/s00702-010-0387-6

Effects of morphine and methadone treatment on mRNA expression of Gα(i) subunits in rat brains

Zelek-Molik, A., Taracha, E., Nawrat, D., Bielawski, A., Lehner, M., Płaźnik, A., Nalepa, I.

DOI: 10.1016/S1734-1140(10)70382-0

Paroxetine pretreatment does not change the effects induced in the rat cortical α-adrenergic receptor system by repetitive transcranial magnetic stimulation and electroconvulsive shock

Vetulani, J., Roman, A., Kowalska, M., Nalepa, I.

DOI: 10.1017/S1461145709990459

Concomitant administration of fluoxetine and amantadine modulates the activity of peritoneal macrophages of rats subjected to a forced swimming test

Roman, A., Rogóz, Z., Kubera, M., Nawrat, D., Nalepa, I.

DOI: 10.1016/S1734-1140(09)70169-0

Chronic treatment with electroconvulsive shock may modulate the immune function of macrophages

Roman, A., Nawrat, D., Nalepa, I.

DOI: 10.1097/YCT.0b013e31816726ae

Head

Grzegorz Kreiner, dr hab.

+48 12 6623335
room 40

See also