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Department of Brain Biochemistry
Scientific profile
- Employees
- Laboratories
Pracownicy zakładu
Professor Irena Nalepa, dr hab.
+48 12 6623225
nalepa@if-pan.krakow.pl
room 39Katarzyna Kuter-Nowak, dr hab.
+48 12 6623226kuter@if-pan.krakow.plroom 3.36Elżbieta Lorenc-Koci, dr hab.
+48 12 6623272lorenc@if-pan.krakow.plroom 338Piotr Chmielarz, dr
+48 12 6623227chmiel@if-pan.krakow.plroom 37ADanuta Jantas, dr hab.
+48 12 3343721jantas@if-pan.krakow.plroom 2.1Agnieszka Zelek-Molik, dr
+48 12 6623227zelek@if-pan.krakow.plroom 36Joanna Kula, dr
+48 12 6623286jkula@if-pan.krakow.plroom 337Justyna Barut, dr
+48 12 6623245jbarut@if-pan.krakow.plroom 43Adam Bielawski, dr
+48 12 6623381bielaw@if-pan.krakow.plroom 37Jolanta Konieczny, dr
+48 12 6623272koniecz@if-pan.krakow.plroom 338Katarzyna Rafa-Zabłocka, dr
+48 12 6623227zablocka@if-pan.krakow.plroom 36Katarzyna Maziarz, mgr
+48 12 6623245maziarz@if-pan.krakow.plroom 43Michał Wilczkowski, mgr
+48 12 6623245wilczkow@if-pan.krakow.plroom 43Anna Alwani, mgr
+48 12 662 32 45alwani@if-pan.krakow.plroom 43Tomasz Lenda, mgr
+48 12 3343709lenda@if-pan.krakow.plroom 340Agata Maziak, dr
+48 12 6623383maziak@if-pan.krakow.plroom 340Emilija Napieralska, mgr
+48 12 3623286napieral@if-pan.krakow.plroom 3.37Pracownicy pracowni
Katarzyna Kuter-Nowak, dr hab.
+48 12 6623226kuter@if-pan.krakow.plroom 3.36Elżbieta Lorenc-Koci, dr hab.
+48 12 6623272lorenc@if-pan.krakow.plroom 338Joanna Kula, dr
+48 12 6623286jkula@if-pan.krakow.plroom 337Tomasz Lenda, mgr
+48 12 3343709lenda@if-pan.krakow.plroom 340Agata Maziak, dr
+48 12 6623383maziak@if-pan.krakow.plroom 340Emilija Napieralska, mgr
+48 12 3623286napieral@if-pan.krakow.plroom 3.37Achievements
- Publications
- Grants
- Awards
Grant
The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopamine receptor ligands
Danuta Jantas, PhD
Grant
PASIFIC Call 1 TheraLanOx "Neuroprotective properties of theranostic lanthanide oxide nanoparticles against neurotoxin-induced cellular models of Parkinson’s disease"
Rugmani Meenambal, PhD
Grant
Hybrid carbon composites for stimulation of cells of the central nervous system
Danuta Jantas, PhD
Grant
Evaluation of the influence of progressive noradrenergic neurodegeneration on dopaminergic system functioning in context of presymptomatic phase of Parkinson's disease
Grzegorz Kreiner, PhD
Grant
Różnicowanie udziału trzech podtypów receptora alfa(1)-adrenergicznego w efektach leków przeciwdepresyjnych: badania w oparciu o genetyczne modele in vitro oraz in vivo OPUS9 2015/17/B/NZ7/03018
Professor Irena Nalepa, PhD
Grant
Zanieczyszczenia powietrza a choroby autoimmunologiczne: rola wielofazowej chemii nieorganicznej SYMFONIA3: APARIC 2015/16/W/ST5/00005
Professor Irena Nalepa, PhD
Grant
Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment
Grzegorz Kreiner, PhD
Grant
The study on the role of metabotropic glutamate receptor subtype 8 (mGluR8) in cancer cells - potential target for new anticancer drugs
Danuta Jantas, PhD
Grant
Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodegeneration, based on tissue specific inducible Cre/loxP system
Grzegorz Kreiner, PhD
Grant
The study on the neuroprotective potential of metabotropic glutamate group II and III receptors in in vitro and in vivo apoptosis models
Danuta Jantas, PhD
Grant
Badanie interakcji szlaków sygnałowych: receptory alfa1-adrenergiczne – stres komórkowy – apoptoza, w modelu chronicznego łagodnego stresu - zadanie 1.4 POIG.01.01.02-12-004/09 DeMeTer (Depresja – Mechanizmy – Terapia) Działanie 1.1 Poddziałanie 1.1.2. Zadanie główne: Modelowanie depresji – strategia poznawania jej etiologii.
Professor Irena Nalepa, PhD
Grant
Badanie interakcji układu noradrenergicznego i glukokortykoidowego w nowym modelu genetycznym i ocena jego przydatności jako modelu depresji u myszy - zadanie 1.2 POIG 01.01.02-12-004/09 DeMeTer (Depresja – Mechanizmy – Terapia). Działanie 1.1 Poddziałanie 1.1.2. Zadanie główne: Modelowanie depresji – strategia poznawania jej etiologii.
Grzegorz Kreiner, PhD
Grant
Funkcja in vitro: funkcjonalna aktywność nowych ligandów receptora serotoninowego 5HT(6) i dopaminowego D(2) na poziomie modulacji odpowiedzi wtórnych przekaźników zadanie nr 6 GRANT POIG ProKog Nr UDA-POIG.01.03.01-12-063/09-02 Działanie 1.3, Poddziałanie 1.3.1: Antagoniści receptora 5HT(6): nowoczesne leki przeciwpsychotyczne o dodatkowym działaniu prokognitywnym
Professor Irena Nalepa, PhD
Award
2020 - Bronze Cross of Merit from President of Poland; for significant contribution to science development in Poland
Danuta Jantas, PhD
Award
Team Scientific Award of the 5th Medical Sciences PAS for a series of 3 publications "The role of astrocytes in mechanisms compensating for the degeneration of dopaminergic neurons and in the regulation of cellular energy of the black-striatal system in an animal model of early Parkinson's disease"
Katarzyna Kuter - Nowak, PhD
Award
2009 - Young Investigator Award, Neuropeptides Festival, Salzburg, Austria.
Danuta Jantas, PhD
Award
Award for publication woth high IF in 2018 granted by the Head of the Institute of Pharmacology
Katarzyna Kuter - Nowak, PhD
Psychosocial Crowding Stress-Induced Changes in Synaptic Transmission and Glutamate Receptor Expression in the Rat Frontal Cortex
Agnieszka Zelek-Molik, Bartosz Bobula, Anna Gądek-Michalska, Katarzyna Chorązka, Adam Bielawski, Justyna Kuśmierczyk, Marcin Siwiec, Michał Wilczkowski, Grzegorz Hess, Irena Nalepa
DOI: 10.3390/biom11020294
Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism
DOI: 10.1038/s41598-019-41756-3
Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury.
DOI: 10.3389/fimmu.2019.02198
Fear memory-induced alterations in the mRNA expression of G proteins in the mouse brain and the impact of immediate posttraining treatment with morphine
DOI: 10.1016/j.pnpbp.2019.04.001
The influence of CaMKII and ERK phosphorylation on BDNF changes observed in mice selectively devoid of CREB in serotonergic or noradrenergic neurons.
DOI: 10.1016/j.pharep.2019.04.008
Assessment of leukocyte activity in mice devoid of the glucocorticoid receptor in the noradrenergic system (GR<sup>DBHCre</sup>)
Roman, A., Kuśmierczyk, J., Kreiner, G., Nalepa, I.
DOI: 10.1016/j.imbio.2017.10.022
Novel multi-target azinesulfonamides of cyclic amine derivatives as potential antipsychotics with pro-social and pro-cognitive effects
Zajdel, P., Kos, T., Marciniec, K., Satała, G., Canale, V., Kamiński, K., Hołuj, M., Lenda, T., Koralewski, R., Bednarski, M., Nowiński, L., Wójcikowski, J., Daniel, W.A., Nikiforuk, A., Nalepa, I., Chmielarz, P., Kuśmierczyk, J., Bojarski, A.J., Popik, P.
DOI: 10.1016/j.ejmech.2018.01.002
Selective Depletion of CREB in Serotonergic Neurons Affects the Upregulation of Brain-Derived Neurotrophic Factor Evoked by Chronic Fluoxetine Treatment
Rafa-Zabłocka, K., Kreiner, G., Baginska, M., Nalepa, I.
DOI: 10.3389/fnins.2018.00637
Involvement of macrophage inflammatory protein-1 family members in the development of diabetic neuropathy and their contribution to effectiveness of morphine
Rojewska, E., Zychowska, M., Piotrowska, A., Kreiner, G., Nalepa, I., Mika, J.
DOI: 10.3389/fimmu.2018.00494
The Protective Effect of Repeated 1MeTIQ Administration on the Lactacystin-Induced Impairment of Dopamine Release and Decline in TH Level in the Rat Brain
Wąsik, A., Romańska, I., Zelek-Molik, A., Nalepa, I., Antkiewicz-Michaluk, L.
DOI: 10.1007/s12640-018-9939-6