Department of Brain Biochemistry
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Department of Brain Biochemistry
Scientific profile
- Employees
- Laboratories
Pracownicy zakładu
Professor Irena Nalepa, dr hab.
Katarzyna Kuter-Nowak, dr hab.
Elżbieta Lorenc-Koci, dr hab.
Piotr Chmielarz, dr
Danuta Jantas, dr hab.
Agnieszka Zelek-Molik, dr
Joanna Kula, dr
Justyna Barut, dr
Adam Bielawski, dr
Jolanta Konieczny, dr
Katarzyna Rafa-Zabłocka, dr
Katarzyna Maziarz, mgr
Michał Wilczkowski, mgr
Anna Alwani, mgr
Tomasz Lenda, mgr
Agata Maziak, dr
Emilija Napieralska, mgr
Pracownicy pracowni
Katarzyna Kuter-Nowak, dr hab.
Elżbieta Lorenc-Koci, dr hab.
Joanna Kula, dr
Tomasz Lenda, mgr
Agata Maziak, dr
Emilija Napieralska, mgr
Achievements
- Publications
- Grants
- Awards
Grant
The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopamine receptor ligands
Danuta Jantas, PhD
Grant
PASIFIC Call 1 TheraLanOx "Neuroprotective properties of theranostic lanthanide oxide nanoparticles against neurotoxin-induced cellular models of Parkinson’s disease"
Rugmani Meenambal, PhD
Grant
Hybrid carbon composites for stimulation of cells of the central nervous system
Danuta Jantas, PhD
Grant
Evaluation of the influence of progressive noradrenergic neurodegeneration on dopaminergic system functioning in context of presymptomatic phase of Parkinson's disease
Grzegorz Kreiner, PhD
Grant
Różnicowanie udziału trzech podtypów receptora alfa(1)-adrenergicznego w efektach leków przeciwdepresyjnych: badania w oparciu o genetyczne modele in vitro oraz in vivo OPUS9 2015/17/B/NZ7/03018
Professor Irena Nalepa, PhD
Grant
Zanieczyszczenia powietrza a choroby autoimmunologiczne: rola wielofazowej chemii nieorganicznej SYMFONIA3: APARIC 2015/16/W/ST5/00005
Professor Irena Nalepa, PhD
Grant
Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment
Grzegorz Kreiner, PhD
Grant
The study on the role of metabotropic glutamate receptor subtype 8 (mGluR8) in cancer cells - potential target for new anticancer drugs
Danuta Jantas, PhD
Grant
Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodegeneration, based on tissue specific inducible Cre/loxP system
Grzegorz Kreiner, PhD
Grant
The study on the neuroprotective potential of metabotropic glutamate group II and III receptors in in vitro and in vivo apoptosis models
Danuta Jantas, PhD
Grant
Badanie interakcji szlaków sygnałowych: receptory alfa1-adrenergiczne – stres komórkowy – apoptoza, w modelu chronicznego łagodnego stresu - zadanie 1.4 POIG.01.01.02-12-004/09 DeMeTer (Depresja – Mechanizmy – Terapia) Działanie 1.1 Poddziałanie 1.1.2. Zadanie główne: Modelowanie depresji – strategia poznawania jej etiologii.
Professor Irena Nalepa, PhD
Grant
Badanie interakcji układu noradrenergicznego i glukokortykoidowego w nowym modelu genetycznym i ocena jego przydatności jako modelu depresji u myszy - zadanie 1.2 POIG 01.01.02-12-004/09 DeMeTer (Depresja – Mechanizmy – Terapia). Działanie 1.1 Poddziałanie 1.1.2. Zadanie główne: Modelowanie depresji – strategia poznawania jej etiologii.
Grzegorz Kreiner, PhD
Grant
Funkcja in vitro: funkcjonalna aktywność nowych ligandów receptora serotoninowego 5HT(6) i dopaminowego D(2) na poziomie modulacji odpowiedzi wtórnych przekaźników zadanie nr 6 GRANT POIG ProKog Nr UDA-POIG.01.03.01-12-063/09-02 Działanie 1.3, Poddziałanie 1.3.1: Antagoniści receptora 5HT(6): nowoczesne leki przeciwpsychotyczne o dodatkowym działaniu prokognitywnym
Professor Irena Nalepa, PhD
Award
2020 - Bronze Cross of Merit from President of Poland; for significant contribution to science development in Poland
Danuta Jantas, PhD
Award
Team Scientific Award of the 5th Medical Sciences PAS for a series of 3 publications "The role of astrocytes in mechanisms compensating for the degeneration of dopaminergic neurons and in the regulation of cellular energy of the black-striatal system in an animal model of early Parkinson's disease"
Katarzyna Kuter - Nowak, PhD
Award
2009 - Young Investigator Award, Neuropeptides Festival, Salzburg, Austria.
Danuta Jantas, PhD
Award
Award for publication woth high IF in 2018 granted by the Head of the Institute of Pharmacology
Katarzyna Kuter - Nowak, PhD
Reversal by imipramine of β-adrenoceptor up-regulation induced in a chronic mild stress model of depression
Papp, M., Nalepa, I., Vetulani, J.
DOI: 10.1016/0014-2999(94)90312-3
Phorbol ester and central chemosympathectomy augment β-adrenoceptor response by different mechanisms
Nalepa, I., Vetulani, J.
DOI:
The antagonistic effect of separate and consecutive chronic treatment with imipramine and ECS on the inhibition of α<inf>1</inf>-adrenoceptor activity by protein kinase C
Nalepa, I., Chalecka-Franaszek, E., Vetulani, J.
DOI:
The effects of chlorpromazine and haloperidol on second messenger systems related to adrenergic receptors
Nalepa, I.
DOI:
The effect of calcium channel blockade on the action of chronic ect and imipramine on responses of α<inf>1</inf>- and β-adrenoceptors in the rat cerebral cortex
Nalepa, I., Vetulani, J.
DOI:
Enhancement of the responsiveness of cortical adrenergic receptors by chronic administration of the 5‐hydroxytryptamine uptake inhibitor citalopram.
Nalepa, I., Vetulani, J.
DOI: 10.1111/j.1471-4159.1993.tb03487.x
Effects of excitatory amino acids on inositol phosphate accumulation in slices of the cerebral cortex of young and aged rats
Nalepa, I., Pintor, A., Chalecka-Franaszek, E., Fortuna, S., Michalek, H., Vetulani, J.
DOI: 10.1007/BF00966935
Centpropazine affinity to cortical noradrenergic receptors and effect on their responsiveness in the rat
DIKSHIT, M., CHALECKA‐FRANASZEK, E., NALEPA, I.
DOI: 10.1111/j.2042-7158.1993.tb05540.x
Effects of diisopropyl fluorophosphate on muscarinic-M1-receptors and on receptor-mediated responsiveness of the phosphatidyl-inositol system in the cerebral cortex of rats
Pintor, A., Fortuna, S., Nalepa, I., Michalek, H.
DOI:
Strain differences in changes in some parameters of cerebral cortical adrenergic system following chronic imipramine administration to rats
Vetulani, J., Nalepa, I., Popik, P.
DOI: