mgr Tomasz Lenda

mgr Tomasz Lenda

+48 12 3343709
pokój 340
Department of Brain Biochemistry

Dokonania naukowe

  • Publikacje

The Effect of Chronic Treatment with the Inhibitor of Phosphodiesterase 5 (PDE5), Sildenafil, in Combination with L-DOPA on Asymmetric Behavior and Monoamine Catabolism in the Striatum and Substantia Nigra of Unilaterally 6-OHDA-Lesioned Rats

Autorzy: Elżbieta Lorenc-Koci, Kinga Kamińska, Tomasz Lenda, Jolanta Konieczny

DOI: 10.3390/molecules29184318
Date: 2024-09-01

Tuning the activity of known drugs via the introduction of halogen atoms, a case study of SERT ligands – Fluoxetine and fluvoxamine

Autorzy:

DOI: 10.1016/j.ejmech.2021.113533
Date: 2021-08-01

<i>N</i>-Skatyltryptamines—Dual 5-HT<sub>6</sub>R/D<sub>2</sub>R Ligands with Antipsychotic and Procognitive Potential

Autorzy: Agata Hogendorf, Adam Hogendorf, Rafał Kurczab, Grzegorz Satała, Bernadeta Szewczyk, Paulina Cieślik, Gniewomir Latacz, Jadwiga Handzlik, Tomasz Lenda, Katarzyna Kaczorowska, Jakub Staroń, Ryszard Bugno, Beata Duszyńska, Andrzej Bojarski

DOI: 10.3390/molecules26154605
Date: 2021-07-01

Rationally designed N-phenylsulfonylindoles as a tool for the analysis of the non-basic 5-HT<sub>6</sub>R ligands binding mode.

Autorzy:

DOI: 10.1016/j.ejmech.2020.112916
Date: 2020-10-09

Inhibition of Excessive Glutamatergic Transmission in the Ventral Thalamic Nuclei by a Selective Adenosine A1 Receptor Agonist, 5'-Chloro-5'-Deoxy-(±)-ENBA Underlies its Tremorolytic Effect in the Harmaline-Induced Model of Essential Tremor.

Autorzy:

DOI: 10.1016/j.neuroscience.2019.12.045
Date: 2020-01-11

Virtual screening-driven discovery of dual 5-HT<sub>6</sub>/5-HT<sub>2A</sub> receptor ligands with pro-cognitive properties.

Autorzy:

DOI: 10.1016/j.ejmech.2019.111857
Date: 2019-11-07

2-Aminoimidazole-based antagonists of the 5-HT<sub>6</sub> receptor - A new concept in aminergic GPCR ligand design.

Autorzy:

DOI: 10.1016/j.ejmech.2019.06.001
Date: 2019-06-05

Fluorinated indole-imidazole conjugates: Selective orally bioavailable 5-HT7 receptor low-basicity agonists, potential neuropathic painkillers.

Autorzy:

DOI: 10.1016/j.ejmech.2019.03.017
Date: 2019-03-11

Neurochemical changes underlying schizophrenia-related behavior in a modified forced swim test in mice

Autorzy: Woźniak, M., Cieślik, P., Marciniak, M., Lenda, T., Pilc, A., Wieronska, J.M.

DOI: 10.1016/j.pbb.2018.06.003
Date: 2018-01-01

Novel multi-target azinesulfonamides of cyclic amine derivatives as potential antipsychotics with pro-social and pro-cognitive effects

Autorzy: Zajdel, P., Kos, T., Marciniec, K., Satała, G., Canale, V., Kamiński, K., Hołuj, M., Lenda, T., Koralewski, R., Bednarski, M., Nowiński, L., Wójcikowski, J., Daniel, W.A., Nikiforuk, A., Nalepa, I., Chmielarz, P., Kuśmierczyk, J., Bojarski, A.J., Popik, P.

DOI: 10.1016/j.ejmech.2018.01.002
Date: 2018-01-01

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