dr Katarzyna Szczepańska

dr Katarzyna Szczepańska

+48 12 6623301
pokój 326
Zakład Chemii Leków

Dokonania naukowe

  • Publikacje

Metabolic benefits of novel histamine H3 receptor ligands in the model of excessive eating: The importance of intrinsic activity and pharmacokinetic properties

Autorzy:

DOI: 10.1016/j.biopha.2021.111952
Date: 2021-10-01

Discovery of Potential, Dual-Active Histamine H3 Receptor Ligands with Combined Antioxidant Properties

Autorzy:

DOI: 10.3390/molecules26082300
Date: 2021-04-15

Structural modifications in the distal, regulatory region of histamine H<sub>3</sub> receptor antagonists leading to the identification of a potent anti-obesity agent.

Autorzy:

DOI: 10.1016/j.ejmech.2020.113041
Date: 2020-11-24

N-Substituted piperazine derivatives as potential multitarget agents acting on histamine H<sub>3</sub> receptor and cancer resistance proteins.

Autorzy:

DOI: 10.1016/j.bmcl.2020.127522
Date: 2020-08-29

Dual-targeting approach on histamine H3 and sigma-1 receptor ligands as promising pharmacological tools in the treatment of CNS-linked disorders.

Autorzy:

DOI: 10.2174/0929867327666200806103144
Date: 2020-08-05

KSK19 - Novel histamine H3 receptor ligand reduces body weight in diet induced obese mice.

Autorzy:

DOI: 10.1016/j.bcp.2019.07.006
Date: 2019-07-08

Structural modifications and in vitro pharmacological evaluation of 4-pyridyl-piperazine derivatives as an active and selective histamine H<sub>3</sub> receptor ligands.

Autorzy:

DOI: 10.1016/j.bioorg.2019.103071
Date: 2019-06-20

Optimization and preclinical evaluation of novel histamine H<sub>3</sub>receptor ligands: Acetyl and propionyl phenoxyalkyl piperazine derivatives.

Autorzy:

DOI: 10.1016/j.bmc.2018.11.010
Date: 2018-11-10

The histamine H3 receptor inverse agonist pitolisant reduces body weight in obese mice.

Autorzy:

DOI: 10.1007/s00210-018-1516-2
Date: 2018-05-25

Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H<sub>3</sub>R ligands.

Autorzy:

DOI: 10.1016/j.ejmech.2018.04.043
Date: 2018-04-25

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