prof. dr hab. Joanna Mika

prof. dr hab. Joanna Mika

+48 12 6623298
pokój 226
Zakład Farmakologii Bólu

Dokonania naukowe

  • Publikacje
  • Granty

Effect of pharmacological modulation of the kynurenine pathway on pain-related behavior and opioid analgesia in a mouse model of neuropathic pain

Autorzy: Katarzyna Ciapała, Katarzyna Pawlik, Agata Ciechanowska, Joanna Mika, Ewelina Rojewska

DOI: 10.1016/j.taap.2023.116382
Date: 2023-02-01

Pharmacological Evidence of the Important Roles of CCR1 and CCR3 and Their Endogenous Ligands CCL2/7/8 in Hypersensitivity Based on a Murine Model of Neuropathic Pain

Autorzy: Katarzyna Pawlik, Katarzyna Ciapała, Agata Ciechanowska, Klaudia Kwiatkowski, Joanna Mika

DOI: 10.3390/cells12010098
Date: 2022-12-26

CC Chemokine Receptor 4 (CCR4) as a Possible New Target for Therapy

Autorzy: Joanna Bogacka, Katarzyna Pawlik, Katarzyna Ciapała, Agata Ciechanowska, Joanna Mika

DOI: 10.3390/ijms232415638
Date: 2022-12-09

Promising anticonvulsant and/or analgesic compounds among 5-chloro-2- or 5-chloro-4-methyl derivatives of xanthone coupled to aminoalkanol moieties - design, synthesis and pharmacological evaluation.

Autorzy: Joanna Mika, Mazur G, Pańczyk-Straszak K, Rapacz A, Kiszela J, Smolik M, Gawlik M, Walczak M, Czekajewska J,

DOI: 10.1111/cbdd.14102
Date: 2022-06-17

Mirogabalin Decreases Pain-like Behaviours and Improves Opioid and Ketamine Antinociception in a Mouse Model of Neuropathic Pain

Autorzy: Renata Zajączkowska, Ewelina Rojewska, Agata Ciechanowska, Katarzyna Pawlik, Katarzyna Ciapała, Magdalena Kocot-Kępska, Wioletta Makuch, Jerzy Wordliczek, Joanna Mika

DOI: 10.3390/ph15010088
Date: 2022-01-13

New insights into the analgesic properties of the XCL1/XCR1 and XCL1/ITGA9 axes modulation under neuropathic pain conditions - evidence from animal studies

Autorzy: Ciechanowska, A., Rojewska, E., Piotrowska, A., Barut, J., Pawlik, K., Ciapała, K., Kreiner, G., Mika, J.

DOI: 10.3389/fimmu.2022.1058204
Date: 2022-01-01

Comparison of the Effects of Chemokine Receptors CXCR2 and CXCR3 Pharmacological Modulation in Neuropathic Pain Model—In Vivo and In Vitro Study

Autorzy: Anna Piotrowska, Katarzyna Ciapała, Katarzyna Pawlik, Klaudia Kwiatkowski, Ewelina Rojewska, Joanna Mika

DOI: 10.3390/ijms222011074
Date: 2021-10-14

The Kynurenine Pathway as a Potential Target for Neuropathic Pain Therapy Design: From Basic Research to Clinical Perspectives

Autorzy: Katarzyna Ciapała, Joanna Mika, Ewelina Rojewska

DOI: 10.3390/ijms222011055
Date: 2021-10-13

Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology

Autorzy:

DOI: 10.1038/s41598-021-89032-7
Date: 2021-05-05

Topical Treatments and Their Molecular/Cellular Mechanisms in Patients with Peripheral Neuropathic Pain—Narrative Review

Autorzy: Magdalena Kocot-Kępska, Renata Zajączkowska, Joanna Mika, David J. Kopsky, Jerzy Wordliczek, Jan Dobrogowski, Anna Przeklasa-Muszyńska

DOI: 10.3390/pharmaceutics13040450
Date: 2021-03-26

Grant

OPUS 22 2021/43/B/NZ7/00230 Nowe strategie w farmakoterapii bólu neuropatycznego oparte na modulacji układu chemokin i jego wpływie na rozwój tolerancji opioidowej

15.07.2022 – 14.07.2026

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