prof. dr hab. Jan Manuel Rodriguez Parkitna

prof. dr hab. Jan Manuel Rodriguez Parkitna

Zastępca Dyrektora ds. Naukowych

+48 12 6623316
pokój 210
Zakład Neurofarmakologii Molekularnej

Dokonania naukowe

  • Publikacje

Addictive drugs and plasticity of glutamatergic synapses on dopaminergic neurons: what have we learned from genetic mouse models?

Autorzy: Rodriguez Parkitna J, Engblom D

DOI: 10.3389/fnmol.2012.00089
Date: 2012-08-01

Novelty-seeking behaviors and the escalation of alcohol drinking after abstinence in mice are controlled by metabotropic glutamate receptor 5 on neurons expressing dopamine d1 receptors.

Autorzy: Parkitna JR, Sikora M, Gołda S, Gołembiowska K, Bystrowska B, Engblom D, Bilbao A, Przewlocki R

DOI: 10.1016/j.biopsych.2012.07.019
Date: 2012-08-01

Ablation of serum response factor in dopaminergic neurons exacerbates susceptibility towards MPTP-induced oxidative stress.

Autorzy: Rieker C, Schober A, Bilbao A, Schütz G, Parkitna JR

DOI: 10.1111/j.1460-9568.2012.08003.x
Date: 2012-02-01

Glutamate input to noradrenergic neurons plays an essential role in the development of morphine dependence and psychomotor sensitization.

Autorzy: Parkitna JR, Solecki W, Gołembiowska K, Tokarski K, Kubik J, Gołda S, Novak M, Parlato R, Hess G, Sprengel R, Przewłocki R

DOI: 10.1017/s1461145711001568
Date: 2011-11-01

Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages.

Autorzy: Kleiman A, Hübner S, Rodriguez Parkitna JM, Neumann A, Hofer S, Weigand MA, Bauer M, Schmid W, Schütz G, Libert C, Reichardt HM, Tuckermann JP

DOI: 10.1096/fj.11-192112
Date: 2011-10-01

Glucocorticoid activity during lung maturation is essential in mesenchymal and less in alveolar epithelial cells.

Autorzy: Habermehl D, Parkitna JR, Kaden S, Brügger B, Wieland F, Gröne HJ, Schütz G

DOI: 10.1210/me.2009-0380
Date: 2011-06-01

MicroRNA loss enhances learning and memory in mice.

Autorzy: Konopka W, Kiryk A, Novak M, Herwerth M, Parkitna JR, Wawrzyniak M, Kowarsch A, Michaluk P, Dzwonek J, Arnsperger T, Wilczynski G, Merkenschlager M, Schütz G

DOI: 10.1523/jneurosci.3030-10.2010
Date: 2010-11-01

Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons.

Autorzy: Novak M, Halbout B, O'Connor EC, Rodriguez Parkitna J, Su T, Chai M, Crombag HS, Bilbao A, Spanagel R, Stephens DN, Schütz G, Engblom D

DOI: 10.1523/jneurosci.2550-10.2010
Date: 2010-09-01

Effects of the cell type-specific ablation of the cAMP-responsive transcription factor in noradrenergic neurons on locus coeruleus firing and withdrawal behavior after chronic exposure to morphine.

Autorzy: Parlato R, Cruz H, Otto C, Murtra P, Parkitna JR, Martin M, Bura SA, Begus-Nahrmann Y, von Bohlen und Halbach O, von Bohlen und Halbach O, Lüscher C

DOI: 10.1111/j.1471-4159.2010.06709.x
Date: 2010-08-01

Loss of the serum response factor in the dopamine system leads to hyperactivity.

Autorzy: Parkitna JR, Bilbao A, Rieker C, Engblom D, Piechota M, Nordheim A, Spanagel R, Schütz G

DOI: 10.1096/fj.09-151423
Date: 2010-03-01

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