Rafał Kurczab, dr hab.

Rafał Kurczab, dr hab.

+48 12 6623301
room 326

Achievements

  • Publications

Data-Driven Analysis of Fluorination of Ligands of Aminergic G Protein Coupled Receptors

Autorzy: Wojciech Pietruś, Rafał Kurczab, Dagmar Stumpfe, Andrzej Bojarski, Jürgen Bajorath

DOI: 10.3390/biom11111647
Date: 2021-11-01

<i>N</i>-Skatyltryptamines—Dual 5-HT<sub>6</sub>R/D<sub>2</sub>R Ligands with Antipsychotic and Procognitive Potential

Autorzy: Agata Hogendorf, Adam Hogendorf, Rafał Kurczab, Grzegorz Satała, Bernadeta Szewczyk, Paulina Cieślik, Gniewomir Latacz, Jadwiga Handzlik, Tomasz Lenda, Katarzyna Kaczorowska, Jakub Staroń, Ryszard Bugno, Beata Duszyńska, Andrzej Bojarski

DOI: 10.3390/molecules26154605
Date: 2021-07-01

Mutual Support of Ligand- and Structure-Based Approaches—To What Extent We Can Optimize the Power of Predictive Model? Case Study of Opioid Receptors

Autorzy: Sabina Podlewska, Rafał Kurczab

DOI: 10.3390/molecules26061607
Date: 2021-03-01

Chlorine substituents and linker topology as factors of 5-HT6R activity for novel highly active 1,3,5-triazine derivatives with procognitive properties in vivo

Autorzy:

DOI:
Date: 2020-07-06

The significance of halogen bonding in ligand-receptor interactions: The lesson learned from molecular dynamic simulations of the D<inf>4</inf> receptor

Autorzy: Kurczab, R., Kucwaj-Brysz, K., Śliwa, P.

DOI: 10.3390/molecules25010091
Date: 2020-01-01

Antifungal, anticancer, and docking studies of colchiceine complexes with monovalent metal cation salts

Autorzy: Kurek, J., Kwaśniewska-Sip, P., Myszkowski, K., Cofta, G., Barczyński, P., Murias, M., Kurczab, R., Śliwa, P., Przybylski, P.

DOI: 10.1111/cbdd.13583
Date: 2019-01-01

Are the hydantoin-1,3,5-triazine 5-HT<inf>6</inf>R ligands a hope to a find new procognitive and anti-obesity drug? Considerations based on primary in vivo assays and ADME-tox profile in vitro

Autorzy: Lubelska, A., Latacz, G., Jastrzȩbska-Wiȩsek, M., Kotańska, M., Kurczab, R., Partyka, A., Maŕc, M.A., Wilczyńska, D., Doroz-Płonka, A., Łazewska, D., Wesołowska, A., Kiéc-Kononowicz, K., Handzlik, J.

DOI: 10.3390/molecules24244472
Date: 2019-01-01

Fluorinated indole-imidazole conjugates: Selective orally bioavailable 5-HT<inf>7</inf> receptor low-basicity agonists, potential neuropathic painkillers

Autorzy: Hogendorf, A.S., Hogendorf, A., Popiołek-Barczyk, K., Ciechanowska, A., Mika, J., Satała, G., Walczak, M., Latacz, G., Handzlik, J., Kieć-Kononowicz, K., Ponimaskin, E., Schade, S., Zeug, A., Bijata, M., Kubicki, M., Kurczab, R., Lenda, T., Staroń, J., Bugno, R., Duszyńska, B., Pilarski, B., Bojarski, A.J.

DOI: 10.1016/j.ejmech.2019.03.017
Date: 2019-01-01

Role of Staple Molecules in the Formation of S···S Contact in Thioamides: Experimental Charge Density and Theoretical Studies

Autorzy: Owczarzak, A., Dutkiewicz, Z., Kurczab, R., Pietruś, W., Kubicki, M., Grześkiewicz, A.M.

DOI: 10.1021/acs.cgd.9b01204
Date: 2019-01-01

Virtual screening-driven discovery of dual 5-HT<inf>6</inf>/5-HT<inf>2A</inf> receptor ligands with pro-cognitive properties

Autorzy: Staroń, J., Kurczab, R., Warszycki, D., Satała, G., Krawczyk, M., Bugno, R., Lenda, T., Popik, P., Hogendorf, A.S., Hogendorf, A., Dubiel, K., Matłoka, M., Moszczyński-Pętkowski, R., Pieczykolan, J., Wieczorek, M., Zajdel, P., Bojarski, A.J.

DOI: 10.1016/j.ejmech.2019.111857
Date: 2019-01-01

See also