dr Piotr Chmielarz

dr Piotr Chmielarz

+48 12 6623227
pokój 37A
Department of Brain Biochemistry

Dokonania naukowe

  • Publikacje

PKB/AKT attenuates Lewy Body-like pathology in primary neurons via Cathepsins B and D

Autorzy: Julia Konovalova, Safak Er, Justyna Barut, Katarzyna Rafa-Zabłocka, Kelvin C. Luk, Małgorzata Figiel, Mikko Airavaara, Andrii Domanskyi, Piotr Chmielarz

DOI: 10.1101/2022.09.23.508066
Date: 2022-09-26

Cell Culture Media, Unlike the Presence of Insulin, Affect α-Synuclein Aggregation in Dopaminergic Neurons

Autorzy: Irena Hlushchuk, Justyna Barut, Mikko Airavaara, Kelvin Luk, Andrii Domanskyi, Piotr Chmielarz

DOI: 10.3390/biom12040563
Date: 2022-04-09

Alpha-synuclein preformed fibrils: a tool to understand Parkinson's disease and develop disease modifying therapy.

Autorzy:

DOI: 10.4103/1673-5374.310686
Date: 2021-11-01

Chronic restraint stress induces changes in the cerebral Galpha 12/13 and Rho-GTPase signaling network

Autorzy: Katarzyna Rafa-Zabłocka, Agnieszka Zelek-Molik, Beata Tepper, Piotr Chmielarz, Grzegorz Kreiner, Michał Wilczkowski, Irena Nalepa

DOI: 10.1007/s43440-021-00294-4
Date: 2021-08-11

Antidepressants Differentially Regulate Intracellular Signaling from α1-Adrenergic Receptor Subtypes In Vitro

Autorzy: Piotr Chmielarz, Justyna Kuśmierczyk, Katarzyna Rafa-Zabłocka, Katarzyna Chorązka, Marta Kowalska, Grzegorz Satała, Irena Nalepa

DOI: 10.3390/ijms22094817
Date: 2021-05-01

Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo

Autorzy: Fernando L. Palhano, Yraima Cordeiro, Kelvin C. Luk, Debora Foguel, Aastha Singh, Liana Shvachiy, Ave Eesmaa, Xu Yan, Gabriela R. Araújo, Katrina Albert, marcius almeida, Mart Saarma, Anne Panhelainen, Diana P. Raymundo, Mikko Airavaara, Merja H. Voutilainen, Tiago F. Outeiro, Henri Juhani Huttunen, Andrii Domanskyi, Piotr Chmielarz

DOI: 10.1016/j.ymthe.2021.04.035
Date: 2021-01-01

Neurotrophic factors for disease-modifying treatments of Parkinson's disease: gaps between basic science and clinical studies

Autorzy: Piotr Chmielarz, Mart Saarma

DOI: 10.1007/s43440-020-00120-3
Date: 2020-10-22

GDNF/RET Signaling Pathway Activation Eliminates Lewy Body Pathology in Midbrain Dopamine Neurons.

Autorzy:

DOI: 10.1002/mds.28258
Date: 2020-09-16

Studying Pre-formed Fibril Induced α-Synuclein Accumulation in Primary Embryonic Mouse Midbrain Dopamine Neurons.

Autorzy:

DOI: 10.3791/61118
Date: 2020-08-16

Back and to the Future: From Neurotoxin-Induced to Human Parkinson's Disease Models.

Autorzy:

DOI: 10.1002/cpns.88
Date: 2020-03-01

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