dr Ewa Bromek

dr Ewa Bromek

+48 12 6623287
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Zakład Farmakokinetyki i Metabolizmu Leków

Dokonania naukowe

  • Publikacje

The Selective NMDA Receptor GluN2B Subunit Antagonist CP-101,606 with Antidepressant Properties Modulates Cytochrome P450 Expression in the Liver

Autorzy: Ewa Bromek, Anna Haduch, Marta Rysz, Joanna Jastrzębska, Renata Pukło, Olga Wójcikowska, Przemysław Jan Danek, Władysława Anna Daniel

DOI: 10.3390/pharmaceutics13101643
Date: 2021-10-09

The Influence of Long-Term Treatment with Asenapine on Liver Cytochrome P450 Expression and Activity in the Rat. The Involvement of Different Mechanisms

Autorzy:

DOI: 10.3390/ph14070629
Date: 2021-06-29

The regulation of liver cytochrome P450 expression and activity by the brain serotonergic system in different experimental models

Autorzy: Ewa Bromek, Władysława Anna Daniel

DOI: 10.1080/17425255.2021.1872543
Date: 2021-04-03

The effects of agomelatine and imipramine on liver cytochrome P450 during chronic mild stress (CMS) in the rat.

Autorzy:

DOI: 10.1007/s43440-020-00151-w
Date: 2020-08-03

Stimulation of 5-HT2C serotonin receptor subtype in the hypothalamic arcuate nuclei (ARC) increases the cytochrome P450 activity in the liver.

Autorzy:

DOI: 10.1016/j.pharep.2019.05.010
Date: 2019-05-17

Serotonin Receptors of 5-HT<sub>2</sub> Type in the Hypothalamic Arcuate Nuclei Positively Regulate Liver Cytochrome P450 via Stimulation of the Growth Hormone-Releasing Hormone/Growth Hormone Hormonal Pathway.

Autorzy:

DOI: 10.1124/dmd.118.083808
Date: 2018-12-05

Activation of 5-HT<inf>1A</inf>receptors in the hypothalamic paraventricular nuclei negatively regulates cytochrome P450 expression and activity in rat liver

Autorzy: Bromek, E., Rysz, M., Haduch, A., Wójcikowski, J., Daniel, W.A.

DOI: 10.1124/dmd.117.079632
Date: 2018-01-01

The reverse role of the hypothalamic paraventricular (PVN) and arcuate (ARC) nuclei in the central serotonergic regulation of the liver cytochrome P450 isoform CYP2C11

Autorzy: Rysz, M., Bromek, E., Haduch, A., Liskova, B., Wójcikowski, J., Daniel, W.A.

DOI: 10.1016/j.bcp.2016.04.017
Date: 2016-01-01

Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain

Autorzy: Haduch, A., Bromek, E., Wójcikowski, J., Gołembiowska, K., Daniel, W.A.

DOI: 10.1124/dmd.115.067413
Date: 2016-01-01

Activation of brain serotonergic system by repeated intracerebral administration of 5-hydroxytryptophan (5-HTP) decreases the expression and activity of liver cytochrome P450

Autorzy: Rysz, M., Bromek, E., Daniel, W.A.

DOI: 10.1016/j.bcp.2015.11.014
Date: 2016-01-01

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