Scientific profile

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Our studies are focused on biologically active secondary metabolites from plants and plant tissue cultures, with special interest in compounds biosynthesized by the plants of Cichorieae and Inuleae tribes (Asteraceae family). Recently, we have been investigating formerly unexamined Lactuca species of African and Asian origin, in a search of antioxidative and anti-inflammatory compounds.

Scope of research

  • plant secondary metabolites – isolation and structure identification/elucidation,
  • qualitative and quantitative analysis of bioactive compounds in a plant material,
  • regulation of plant metabolism in vitro and in vivo,
  • bioactivity assays,
  • tissue cultures of medicinal plants.

In cooperation with other research teams and institutions we perform analyses of selected compounds in a plant material of different origin, provide pure compounds for bioactivity evaluation and share plant materials for biological studies.

Achievements

  • Publications

Lactuca racemosa Willd., Source of Antioxidants with Diverse Chemical Structures

Klaudia Michalska, Danuta Jantas, Janusz Malarz, Klaudia Jakubowska, Wojciech Paul, Anna Stojakowska

DOI: 10.3390/molecules29245975

Composition and Activities of Carpesium macrocephalum Franch. & Sav. Essential Oils

Anna Wajs-Bonikowska, Janusz Malarz, Łukasz Szoka, Paweł Kwiatkowski, Anna Stojakowska

DOI: 10.3390/molecules29194658

Selectivity Screening and Structure–Cytotoxic Activity Observations of Selected Oleanolic Acid (OA)-Type Saponins from the Amaranthaceae Family on a Wide Panel of Human Cancer Cell Lines

Karolina Grabowska, Agnieszka Galanty, Łukasz Pecio, Anna Stojakowska, Janusz Malarz, Paweł Żmudzki, Paweł Zagrodzki, Irma Podolak

DOI: 10.3390/molecules29163794

Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

Janusz Malarz, Klaudia Michalska, Anna Stojakowska

DOI: 10.3390/molecules29092014

Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

Janusz Malarz, Klaudia Michalska, Anna Stojakowska

DOI: 10.20944/preprints202404.0352.v1

Bioprospecting of the Telekia speciosa: Uncovering the Composition and Biological Properties of Its Essential Oils

Anna Wajs-Bonikowska, Łukasz Szoka, Paweł Kwiatkowski, Surya Nandan Meena, Anna Stojakowska

DOI: 10.3390/app13095674

Constituents of Pulicaria inuloides and Cytotoxic Activities of Two Methoxylated Flavonols

Janusz Malarz, Klaudia Michalska, Agnieszka Galanty, Anna Karolina Kiss, Anna Stojakowska

DOI: 10.3390/molecules28020480

Chemical Composition and Cytotoxic Activity of Extracts from Carpesium divaricatum: In Vitro- versus Field-Grown Plants

Janusz Malarz, Agnieszka Galanty, Anna Stojakowska

DOI: 10.3390/plants11212815

See also