Laboratory of Neurobiology of Psychiatric Disorders

Scientific profile

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Research profile

The Laboratory of Neurobiology of Psychiatric Disorders was established in 2010 to conduct extensive research regarding the significance of trace elements in the regulation of central nervous system function, in particular their role in the development and therapy of affective disorders.

The principal objective of our research is zinc. For over a decade we have been studying the importance of this bioelement in the pathophysiology and treatment of depression. Our studies have demonstrated that zinc exhibits antidepressant-like properties and may positively modulate / enhance the activity of other antidepressants. Currently, we are investigating the neurobiological and behavioral aspects of zinc deficiency as a potential new animal model of depression.

Our laboratory closely cooperates with other scientific units (including AGH University of Science and Technology, Department of Psychiatry Jagiellonian University Medical College (UJCM), Department of Pharmacobiology UJCM, Faculty of Chemistry UJ, the Institute of Forensic Research, Medical University of Lublin, the Center for Microelectronics and Nanotechnology University of Rzeszów). Through this collaboration we are developing new experimental methods and techniques enabling more comprehensive and multidimensional research approach.

Joanna Wieronska

Joanna Wieronska, dr hab.

Head

+48 12 6623288
room 313

Pracownicy zakładu

Michał Santocki, dr

Achievements

  • Publications
  • Grants

Grant

Grant

Grant

Partial mGlu<sub>5</sub> receptor NAM, M-5MPEP, induces rapid and sustained antidepressant-like effects in the BDNF-dependent mechanism and enhances (R)-ketamine action in mice.

Agnieszka Pałucha-Poniewiera, Rafało-Ulińska A, Santocki M, Babii Y, Kaczorowska K

DOI: 10.1007/s43440-024-00588-3

Impact of endogenous and exogenous nitrogen species on macrophage extracellular trap (MET) formation by bone marrow-derived macrophages.

Drab D, Santocki M, Opydo M, Elzbieta Kolaczkowska

DOI: 10.1007/s00441-023-03832-z

The search towards cyto-embryological and physiological obstacles in sexual reproduction of Stevia rebaudiana Bertoni

Monika Tuleja, Michał Santocki, Michal Dziurka, Krystyna Musiał, Ewa Capecka, Marta Libik-Konieczny

DOI: 10.1016/j.scienta.2021.110342

Scrutinizing Mechanisms of the ‘Obesity Paradox in Sepsis’: Obesity Is Accompanied by Diminished Formation of Neutrophil Extracellular Traps (NETs) Due to Restricted Neutrophil–Platelet Interactions

Iwona Cichon, Weronika Ortmann, Michal Santocki, Malgorzata Opydo-Chanek, Elzbieta Kolaczkowska

DOI: 10.3390/cells10020384

On Neutrophil Extracellular Trap (NET) Removal: What We Know Thus Far and Why So Little

Michal Santocki, Elzbieta Kolaczkowska

DOI: 10.3390/cells9092079

Imaging of Neutrophils and Neutrophil Extracellular Traps (NETs) with Intravital (In Vivo) Microscopy.

Cichon I, Santocki M, Ortmann W, Kolaczkowska E

DOI: 10.1007/978-1-0716-0154-9_26

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps.

Sebastian Boeltz, Amini P, Anders HJ, Andrade F, Rostyslav Bilyy, Chatfield S, Cichon I, Clancy DM, Jyaysi desai, Dumych T, Dwivedi N, Rachael Gordon, Jonas Hahn, Andrés Hidalgo, MH Hoffmann, Kaplan MJ, Knight JS, Kolaczkowska E, Kubes P, Moritz Leppkes, Manfredi AA, Seamus Martin, Christian Maueröder, Norma Maugeri, Mitroulis I, Luis E. Munoz, Nakazawa D, Neeli I, Nizet V, Pieterse E, Marko Radic, Reinwald C, Ritis K, Rovere-Querini P, Santocki M, Schauer C, Schett G, Shlomchik MJ, Hans-Uwe Simon, Panagiotis Skendros, Darko Stojkov, Peter Vandenabeele, Berghe TV, van der Vlag J, Vitkov L, Maren von Köckritz-Blickwede, Shida Yousefi, Zarbock A, Martin Herrmann

DOI: 10.1038/s41418-018-0261-x

Restoration of experimentally depleted coelomocytes in juvenile and adult composting earthworms Eisenia andrei E. fetida and Dendrobaena veneta

Michal Santocki, Andrzej Falniowski, Barbara Plytycz

DOI: 10.1016/j.apsoil.2015.08.022

Differential Time Course of Restoration of Experimentally Depleted Coelomocytes and Fluorophores in the Earthworm Eisenia Andrei.

Santocki M, Morgan AJ, Barbara Plytycz

DOI: 10.3409/fb64_2.121

Exosomes as mediators of intercellular communication: clinical implications.

Katarzyna Nazimek, Krzysztof Bryniarski, Santocki M, Ptak W

DOI: 10.20452/pamw.2840

Head

Joanna Wierońska, dr hab.

+48 12 6623288
room 313

See also